1MHK

Crystal Structure Analysis of a 26mer RNA molecule, representing a new RNA motif, the hook-turn

1MHK の概要

• エントリーDOI: 10.2210/pdb1mhk/pdb
• 分子名称: RNA 12-mer BCh12, RNA 14-mer BCh12, BROMIDE ION, ... (4 entities in total)
• 機能のキーワード: helix, 180 degree turn, rna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 8369.95

構造登録者

Szep, S.,Wang, J.,Moore, P.B. (登録日: 2002-08-20, 公開日: 2002-09-06, 最終更新日: 2024-02-14)

主引用文献

Szep, S.,Wang, J.,Moore, P.B.
The crystal structure of a 26-nucleotide RNA containing a hook-turn
RNA, 9:44-51, 2003

PubMed Abstract: A crystal structure has been obtained for a 26-nucleotide RNA that contains the loop E sequence from Chromatium minutissimum. Rather than having a loop E-like conformation, it consists of an A-form helix that splits into two separate strands following a sheared A-G base pair. The backbone of the strand containing the G of the A-G pair makes a turn of almost 180 degrees in the space of two nucleotides, and then interacts with the minor groove of the helix from which it originates. Similar structures, which we call hook-turns, occur in 16S and 23S rRNAs. They are found at places where the two strands of a helix separate at an A/G juxtaposition to interact with other sequences.

PubMed: 12554875
DOI: 10.1261/rna.2107303

実験手法

X-RAY DIFFRACTION (2.5 Å)