1MHJ

SOLUTION STRUCTURE OF THE SUPERACTIVE MONOMERIC DES-[PHE(B25)] HUMAN INSULIN MUTANT. ELUCIDATION OF THE STRUCTURAL BASIS FOR THE MONOMERIZATION OF THE DES-[PHE(B25)] INSULIN AND THE DIMERIZATION OF NATIVE INSULIN

1MHJ の概要

• エントリーDOI: 10.2210/pdb1mhj/pdb
• 分子名称: INSULIN (2 entities in total)
• 機能のキーワード: hormone
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P01308 P01308
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 5670.48

構造登録者

Jorgensen, A.M.M.,Olsen, H.B.,Led, J.J.,Balschmidt, P. (登録日: 1994-11-30, 公開日: 1995-10-15, 最終更新日: 2017-11-29)

• 主引用文献: Jorgensen, A.M.,Olsen, H.B.,Balschmidt, P.,Led, J.J.; Solution structure of the superactive monomeric des-[Phe(B25)] human insulin mutant: elucidation of the structural basis for the monomerization of des-[Phe(B25)] insulin and the dimerization of native insulin.; J.Mol.Biol., 257:684-699, 1996; PubMed: 8648633; DOI: 10.1006/jmbi.1996.0194

実験手法

SOLUTION NMR