1MH1

SMALL G-PROTEIN

Summary for 1MH1

Entry DOI	10.2210/pdb1mh1/pdb
Descriptor	RAC1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (4 entities in total)
Functional Keywords	gtp-binding, gtpase, small g-protein, rho family, ras super family
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity): P63000
Total number of polymer chains	1
Total formula weight	21059.20
Authors	Hirshberg, M.,Stockley, R.W.,Dodson, G.,Webb, M.R. (deposition date: 1997-01-21, release date: 1998-01-21, Last modification date: 2024-05-22)
Primary citation	Hirshberg, M.,Stockley, R.W.,Dodson, G.,Webb, M.R. The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue. Nat.Struct.Biol., 4:147-152, 1997 Cited by PubMed Abstract: The crystal structure of human rac1, a member of the rho family of small G-proteins, complexed with the non-hydrolysable GTP analogue, guanosine-5'-(beta gamma-imino)triphosphate (GMPPNP), has been determined by X-ray analysis at a resolution of 1.38 A. Comparison with the structure of H-ras indicates that rac1 has an extra alpha-helical domain that is characteristic of the rho G proteins, and may be involved in the signalling pathway of this family. PubMed: 9033596 DOI: 10.1038/nsb0297-147 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.38 Å)

Structure validation