1MF2

ANTI HIV1 PROTEASE FAB COMPLEX

Summary for 1MF2

DescriptorMONOCLONAL ANTIBODY F11.2.32 (3 entities in total)
Functional Keywordsfab fragment, cross-reactivity, hiv1 protease, enzyme inhibition, immunoglobulin
Biological sourceMus musculus (house mouse)
Total number of polymer chains4
Total molecular weight95942.87
Authors
Lescar, J.,Bentley, G.A. (deposition date: 1996-12-27, release date: 1997-12-31, Last modification date: 2011-07-13)
Primary citation
Lescar, J.,Stouracova, R.,Riottot, M.M.,Chitarra, V.,Brynda, J.,Fabry, M.,Horejsi, M.,Sedlacek, J.,Bentley, G.A.
Three-dimensional structure of an Fab-peptide complex: structural basis of HIV-1 protease inhibition by a monoclonal antibody.
J.Mol.Biol., 267:1207-1222, 1997
PubMed: 9150407 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.1997.0950
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.209180.9%8.5%0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report