1MEN

complex structure of human GAR Tfase and substrate beta-GAR

Summary for 1MEN

Entry DOI	10.2210/pdb1men/pdb
Related	1MEJ 1MEO
Descriptor	Phosphoribosylglycinamide formyltransferase, GLYCINAMIDE RIBONUCLEOTIDE (3 entities in total)
Functional Keywords	purine biosynthesis, substrate-enzyme complex, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	3
Total formula weight	73220.38
Authors	Zhang, Y.,Desharnais, J.,Greasley, S.E.,Beardsley, G.P.,Boger, D.L.,Wilson, I.A. (deposition date: 2002-08-08, release date: 2002-12-18, Last modification date: 2023-09-20)
Primary citation	Zhang, Y.,Desharnais, J.,Greasley, S.E.,Beardsley, G.P.,Boger, D.L.,Wilson, I.A. Crystal structures of human GAR Tfase of low and high pH and with substrate beta-GAR Biochemistry, 41:14206-14215, 2002 Cited by PubMed: 12450384 DOI: 10.1021/bi020522m PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.23 Å)

Structure validation