1MC0
Regulatory Segment of Mouse 3',5'-Cyclic Nucleotide Phosphodiesterase 2A, Containing the GAF A and GAF B Domains
Summary for 1MC0
Entry DOI | 10.2210/pdb1mc0/pdb |
Descriptor | 3',5'-cyclic nucleotide phosphodiesterase 2A, CYCLIC GUANOSINE MONOPHOSPHATE (3 entities in total) |
Functional Keywords | gaf domain, 3', 5'-cyclic nucleotide phosphodiesterase, 5'-guanosine monophosphate, hydrolase |
Biological source | Mus musculus (house mouse) |
Cellular location | Membrane; Peripheral membrane protein (Potential): Q922S4 |
Total number of polymer chains | 1 |
Total formula weight | 41769.12 |
Authors | Martinez, S.,Wu, A.,Glavas, N.,Tang, X.,Turley, S.,Hol, W.,Beavo, J. (deposition date: 2002-08-04, release date: 2002-10-02, Last modification date: 2011-07-13) |
Primary citation | Martinez, S.E.,Wu, A.Y.,Glavas, N.A.,Tang, X.B.,Turley, S.,Hol, W.G.,Beavo, J.A. The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding. Proc.Natl.Acad.Sci.USA, 99:13260-13265, 2002 Cited by PubMed: 12271124DOI: 10.1073/pnas.192374899 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.86 Å) |
Structure validation
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