1MA3

Structure of a Sir2 enzyme bound to an acetylated p53 peptide

1MA3 の概要

• エントリーDOI: 10.2210/pdb1ma3/pdb
• 分子名称: Transcriptional regulatory protein, Sir2 family, Cellular tumor antigen p53, ZINC ION, ... (5 entities in total)
• 機能のキーワード: enzyme-substrate complex, protein binding, transcription
• 由来する生物種: Archaeoglobus fulgidus; 詳細
• 細胞内の位置: Cytoplasm (Probable): O30124; Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 30937.17

構造登録者

Avalos, J.L.,Celic, I.,Muhammad, S.,Cosgrove, M.S.,Boeke, J.D.,Wolberger, C. (登録日: 2002-07-31, 公開日: 2002-10-16, 最終更新日: 2011-07-13)

• 主引用文献: Avalos, J.L.,Celic, I.,Muhammad, S.,Cosgrove, M.S.,Boeke, J.D.,Wolberger, C.; Structure of a Sir2 enzyme bound to an acetylated p53 peptide; Mol.Cell, 10:523-535, 2002; PubMed: 12408821; DOI: 10.1016/S1097-2765(02)00628-7

実験手法

X-RAY DIFFRACTION (2 Å)