1M7I
CRYSTAL STRUCTURE OF A MONOCLONAL FAB SPECIFIC FOR SHIGELLA FLEXNERI Y LIPOPOLYSACCHARIDE COMPLEXED WITH A PENTASACCHARIDE
Summary for 1M7I
Entry DOI | 10.2210/pdb1m7i/pdb |
Related | 1M71 1M7D 1MCP |
Descriptor | light chain of the monoclonal antibody Fab SYA/J6, heavy chain of the monoclonal antibody Fab SYA/J6, alpha-L-rhamnopyranose-(1-2)-alpha-L-rhamnopyranose-(1-3)-alpha-L-rhamnopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-methyl 6-deoxy-alpha-L-rhamnopyranoside, ... (4 entities in total) |
Functional Keywords | fab-carbohydrate interactions; shigella o-antigen; and anti-carbohydrate antibody, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 48084.51 |
Authors | Vyas, N.K.,Vyas, M.N.,Chervenak, M.C.,Johnson, M.A.,Pinto, B.M.,Bundle, D.R.,Quiocho, F.A. (deposition date: 2002-07-19, release date: 2003-07-22, Last modification date: 2020-07-29) |
Primary citation | Vyas, N.K.,Vyas, M.N.,Chervenak, M.C.,Johnson, M.A.,Pinto, B.M.,Bundle, D.R.,Quiocho, F.A. Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for Shigella flexneri Y Lipopolysaccharide: X-ray Structures and Thermodynamics Biochemistry, 41:13575-13586, 2002 Cited by PubMed: 12427018DOI: 10.1021/bi0261387 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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