1M54

CYSTATHIONINE-BETA SYNTHASE: REDUCED VICINAL THIOLS

1M54 の概要

• エントリーDOI: 10.2210/pdb1m54/pdb
• 関連するPDBエントリー: 1JBQ
• 分子名称: CYSTATHIONINE BETA-SYNTHASE, PYRIDOXAL-5'-PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total)
• 機能のキーワード: plp protein fold type ii (tryptophan synthase), plp and heme bound to protein, reduced vicinal cysteines, lyase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P35520
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 244718.14

構造登録者

Taoka, S.,Lepore, B.W.,Kabil, O.,Ojha, S.,Ringe, D.,Banerjee, R. (登録日: 2002-07-08, 公開日: 2002-08-14, 最終更新日: 2021-10-27)

• 主引用文献: Taoka, S.,Lepore, B.W.,Kabil, O.,Ojha, S.,Ringe, D.,Banerjee, R.; HUMAN CYSTATHIONINE BETA-SYNTHASE IS A HEME SENSOR PROTEIN. EVIDENCE THAT THE REDOX SENSOR IS HEME AND NOT THE VICINAL CYSTEINES IN THE CXXC MOTIF SEEN IN THE CRYSTAL STRUCTURE OF THE TRUNCATED ENZYME; BIOCHEMISTRY, 41:10454-10461, 2002; PubMed: 12173932; DOI: 10.1021/bi026052d

実験手法

X-RAY DIFFRACTION (2.9 Å)