1M18
LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA
Summary for 1M18
Entry DOI | 10.2210/pdb1m18/pdb |
Related | 1AOI 1M19 1M1A |
Descriptor | Palindromic 146 Base Pair DNA Fragment, Histone H3.2, Histone H4, ... (8 entities in total) |
Functional Keywords | nucleosome, chromatin, histone, pyrrole-imidazole polyamide, dna regognition, chromatin remodeling, structural protein-dna complex, structural protein/dna |
Biological source | Xenopus laevis (African clawed frog) More |
Cellular location | Nucleus: P02302 P06897 P02281 |
Total number of polymer chains | 10 |
Total formula weight | 201945.85 |
Authors | Suto, R.K.,Edayathumangalam, R.S.,White, C.L.,Melander, C.,Gottesfeld, J.M.,Dervan, P.B.,Luger, K. (deposition date: 2002-06-18, release date: 2003-02-18, Last modification date: 2024-02-14) |
Primary citation | Suto, R.K.,Edayathumangalam, R.S.,White, C.L.,Melander, C.,Gottesfeld, J.M.,Dervan, P.B.,Luger, K. Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands J.Mol.Biol., 326:371-380, 2003 Cited by PubMed: 12559907DOI: 10.1016/S0022-2836(02)01407-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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