1LVO

Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain

1LVO の概要

• エントリーDOI: 10.2210/pdb1lvo/pdb
• 分子名称: Replicase, hydrolase domain, SULFATE ION, 1,4-DIETHYLENE DIOXIDE, ... (5 entities in total)
• 機能のキーワード: 3c like, corona, proteinase, chymotrypsin, cysteine histidine dyad, beta barrel, hydrolase
• 由来する生物種: Transmissible gastroenteritis virus
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 202836.08

構造登録者

Anand, K.,Palm, G.J.,Mesters, J.R.,Siddell, S.G.,Ziebuhr, J.,Hilgenfeld, R. (登録日: 2002-05-29, 公開日: 2002-07-17, 最終更新日: 2024-03-13)

• 主引用文献: Anand, K.,Palm, G.J.,Mesters, J.R.,Siddell, S.G.,Ziebuhr, J.,Hilgenfeld, R.; Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain.; EMBO J., 21:3213-3224, 2002; PubMed: 12093723; DOI: 10.1093/emboj/cdf327

実験手法

X-RAY DIFFRACTION (1.96 Å)