1LVJ

STRUCTURE OF TAR RNA COMPLEXED WITH A TAT-TAR INTERACTION NANOMOLAR INHIBITOR THAT WAS IDENTIFIED BY COMPUTATIONAL SCREENING

1LVJ の概要

• エントリーDOI: 10.2210/pdb1lvj/pdb
• 分子名称: HIV-1 Trans Activating Region RNA, 1-[10-(3-DIMETHYLAMINO-PROPYL)-10H-PHENOTHIAZIN-2-YL]-ETHANONE (2 entities in total)
• 機能のキーワード: transcriptional activation, complex (rna-drug), rna
• 由来する生物種: Human immunodeficiency virus 1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 10284.40

構造登録者

Du, Z.,Lind, K.E.,James, T.L. (登録日: 2002-05-28, 公開日: 2002-12-11, 最終更新日: 2022-02-23)

• 主引用文献: Du, Z.,Lind, K.E.,James, T.L.; Structure of TAR RNA complexed with a Tat-TAR interaction nanomolar inhibitor that was identified by computational screening; CHEM.BIOL., 9:707-712, 2002; PubMed: 12079782; DOI: 10.1016/S1074-5521(02)00151-5

実験手法

SOLUTION NMR