1LV8

Crystal structure of calf spleen purine nucleoside phosphorylase in a new space group with full trimer in the asymmetric unit

Summary for 1LV8

Entry DOI	10.2210/pdb1lv8/pdb
Related	1FXU 1LVU
Descriptor	PURINE NUCLEOSIDE PHOSPHORYLASE, CALCIUM ION, 2,6-DIAMINO-(S)-9-[2-(PHOSPHONOMETHOXY)PROPYL]PURINE, ... (4 entities in total)
Functional Keywords	pnp, purie nucleoside phosphorylase, pentosyltransferase, ne 2, 6-diaminopurine multisubstrate analogue inhibitor, transferase
Biological source	Bos taurus (cattle)
Cellular location	Cytoplasm, cytoskeleton (By similarity): P55859
Total number of polymer chains	6
Total formula weight	194801.08
Authors	Bzowska, A.,Koellner, G.,Wielgus-Kutrowska, B.,Stroh, A.,Raszewski, G.,Holy, A.,Steiner, T.,Frank, J. (deposition date: 2002-05-27, release date: 2003-09-02, Last modification date: 2023-10-25)
Primary citation	Bzowska, A.,Koellner, G.,Wielgus-Kutrowska, B.,Stroh, A.,Raszewski, G.,Holy, A.,Steiner, T.,Frank, J. Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: important implications for the mechanism of catalysis J.Mol.Biol., 342:1015-1032, 2004 Cited by PubMed: 15342253 DOI: 10.1016/j.jmb.2004.07.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation