1LV8

Crystal structure of calf spleen purine nucleoside phosphorylase in a new space group with full trimer in the asymmetric unit

1LV8 の概要

• エントリーDOI: 10.2210/pdb1lv8/pdb
• 関連するPDBエントリー: 1FXU 1LVU
• 分子名称: PURINE NUCLEOSIDE PHOSPHORYLASE, CALCIUM ION, 2,6-DIAMINO-(S)-9-[2-(PHOSPHONOMETHOXY)PROPYL]PURINE, ... (4 entities in total)
• 機能のキーワード: pnp, purie nucleoside phosphorylase, pentosyltransferase, ne 2, 6-diaminopurine multisubstrate analogue inhibitor, transferase
• 由来する生物種: Bos taurus (cattle)
• 細胞内の位置: Cytoplasm, cytoskeleton (By similarity): P55859
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 194801.08

構造登録者

Bzowska, A.,Koellner, G.,Wielgus-Kutrowska, B.,Stroh, A.,Raszewski, G.,Holy, A.,Steiner, T.,Frank, J. (登録日: 2002-05-27, 公開日: 2003-09-02, 最終更新日: 2023-10-25)

• 主引用文献: Bzowska, A.,Koellner, G.,Wielgus-Kutrowska, B.,Stroh, A.,Raszewski, G.,Holy, A.,Steiner, T.,Frank, J.; Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: important implications for the mechanism of catalysis; J.Mol.Biol., 342:1015-1032, 2004; PubMed: 15342253; DOI: 10.1016/j.jmb.2004.07.017

実験手法

X-RAY DIFFRACTION (2.3 Å)