1LV5

Crystal Structure of the Closed Conformation of Bacillus DNA Polymerase I Fragment Bound to DNA and dCTP

1LV5 の概要

• エントリーDOI: 10.2210/pdb1lv5/pdb
• 関連するPDBエントリー: 1L3S 1L3T 1L3U 1L3V 1L5U
• 分子名称: 5'-D(*GP*GP*AP*TP*CP*AP*GP*CP*GP*A)-3', 5'-D(*AP*CP*GP*TP*CP*GP*CP*TP*GP*AP*TP*CP*CP*G)-3', DNA POLYMERASE I, ... (8 entities in total)
• 機能のキーワード: dna polymerase i, dna replication, klenow fragment, protein-dna-dntp complex, closed conformation, transferase-dna complex, transferase/dna
• 由来する生物種: Geobacillus stearothermophilus
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 148219.91

構造登録者

Johnson, S.J.,Taylor, J.S.,Beese, L.S. (登録日: 2002-05-24, 公開日: 2003-03-25, 最終更新日: 2024-02-14)

• 主引用文献: Johnson, S.J.,Taylor, J.S.,Beese, L.S.; Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations; Proc.Natl.Acad.Sci.USA, 100:3895-3900, 2003; PubMed: 12649320; DOI: 10.1073/pnas.0630532100

実験手法

X-RAY DIFFRACTION (1.95 Å)