1LS6
Human SULT1A1 complexed with PAP and p-Nitrophenol
Summary for 1LS6
Entry DOI | 10.2210/pdb1ls6/pdb |
Descriptor | aryl sulfotransferase, ADENOSINE-3'-5'-DIPHOSPHATE, P-NITROPHENOL, ... (4 entities in total) |
Functional Keywords | sult 1a1, pap, p-nitrophenol, positive cooperativity, two substrate binding sites, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P50225 |
Total number of polymer chains | 1 |
Total formula weight | 34925.73 |
Authors | Gamage, N.U.,Barnett, A.C.,Tresillian, M.,Latham, C.F.,Liyou, N.E.,McManus, M.E.,Martin, J.L. (deposition date: 2002-05-17, release date: 2003-08-05, Last modification date: 2024-02-14) |
Primary citation | Gamage, N.U.,Duggleby, R.G.,Barnett, A.C.,Tresillian, M.,Latham, C.F.,Liyou, N.E.,McManus, M.E.,Martin, J.L. Structure of a human carcinogen-converting enzyme, SULT1A1. Structural and kinetic implications of substrate inhibition. J.Biol.Chem., 278:7655-7662, 2003 Cited by PubMed: 12471039DOI: 10.1074/jbc.M207246200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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