1LIS

THE CRYSTAL STRUCTURE OF A FERTILIZATION PROTEIN

1LIS の概要

• エントリーDOI: 10.2210/pdb1lis/pdb
• 分子名称: LYSIN (2 entities in total)
• 機能のキーワード: fertilization protein
• 由来する生物種: Haliotis rufescens (California red abalone)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16295.22

構造登録者

Shaw, A.,Mcree, D.E.,Vacquier, V.D.,Stout, C.D. (登録日: 1993-06-29, 公開日: 1993-10-31, 最終更新日: 2024-02-14)

主引用文献

Shaw, A.,McRee, D.E.,Vacquier, V.D.,Stout, C.D.
The crystal structure of lysin, a fertilization protein.
Science, 262:1864-1867, 1993

PubMed Abstract: Lysin, a protein from abalone sperm, creates a hole in the envelope of the egg, permitting the sperm to pass through the envelope and fuse with the egg. The structure of lysin, refined at 1.9 angstroms resolution, reveals an alpha-helical, amphipathic molecule. The surface of the protein exhibits three features: two tracks of basic residues that span the length of the molecule, a solvent-exposed cluster of aromatic and aliphatic amino acids, and an extended amino-terminal hypervariable domain that is species-specific. The structure suggests possible mechanisms of action.

PubMed: 8266073

実験手法

X-RAY DIFFRACTION (1.9 Å)