1LE2
STRUCTURAL BASIS FOR ALTERED FUNCTION IN THE COMMON MUTANTS OF HUMAN APOLIPOPROTEIN-E
Summary for 1LE2
Entry DOI | 10.2210/pdb1le2/pdb |
Descriptor | APOLIPOPROTEIN E2 (1 entity in total) |
Functional Keywords | lipoprotein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02649 |
Total number of polymer chains | 1 |
Total formula weight | 16689.03 |
Authors | Wilson, C.,Agard, D.A. (deposition date: 1991-08-22, release date: 1992-10-15, Last modification date: 2024-02-14) |
Primary citation | Wilson, C.,Mau, T.,Weisgraber, K.H.,Wardell, M.R.,Mahley, R.W.,Agard, D.A. Salt bridge relay triggers defective LDL receptor binding by a mutant apolipoprotein. Structure, 2:713-718, 1994 Cited by PubMed: 7994571DOI: 10.1016/S0969-2126(00)00072-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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