1LB8
Crystal structure of the Non-desensitizing GluR2 ligand binding core mutant (S1S2J-L483Y) in complex with AMPA at 2.3 resolution
Summary for 1LB8
Entry DOI | 10.2210/pdb1lb8/pdb |
Descriptor | Glutamate receptor 2, (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID (3 entities in total) |
Functional Keywords | ampa receptor, glur2, s1s2, ligand-binding core, non-desensitizing, point mutation, l483y, agonist, membrane protein |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P19491 |
Total number of polymer chains | 2 |
Total formula weight | 58915.73 |
Authors | Sun, Y.,Olson, R.,Horning, M.,Armstrong, N.,Mayer, M.,Gouaux, E. (deposition date: 2002-04-02, release date: 2002-06-05, Last modification date: 2023-08-16) |
Primary citation | Sun, Y.,Olson, R.,Horning, M.,Armstrong, N.,Mayer, M.,Gouaux, E. Mechanism of glutamate receptor desensitization. Nature, 417:245-253, 2002 Cited by PubMed: 12015593DOI: 10.1038/417245a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report