1L7T
Crystal Structure Analysis of the anti-testosterone Fab fragment
Summary for 1L7T
Entry DOI | 10.2210/pdb1l7t/pdb |
Related | 1L7S |
Descriptor | anti-testosterone (light chain), anti-testosterone (heavy chain) (3 entities in total) |
Functional Keywords | anti-testosterone, fab fragment, affinity and specificity matured, immune system |
Biological source | Mus musculus (house mouse) More |
Cellular location | Cell membrane ; Single-pass membrane protein : P01869 |
Total number of polymer chains | 2 |
Total formula weight | 47735.61 |
Authors | Valjakka, J.,Hemminki, A.,Niemi, S.,Soderlund, H.,Takkinen, K.,Rouvinen, J. (deposition date: 2002-03-17, release date: 2002-10-02, Last modification date: 2018-04-04) |
Primary citation | Valjakka, J.,Hemminki, A.,Niemi, S.,Soderlund, H.,Takkinen, K.,Rouvinen, J. Crystal Structure of an in Vitro Affinity- and Specificity-matured Anti-testosterone Fab in Complex with Testosterone. IMPROVED AFFINITY RESULTS FROM SMALL STRUCTURAL CHANGES WITHIN THE VARIABLE DOMAINS J.Biol.Chem., 277:44021-44027, 2002 Cited by PubMed: 12196551DOI: 10.1074/jbc.M208392200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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