1L7I
Crystal Structure of the anti-ErbB2 Fab2C4
Summary for 1L7I
Entry DOI | 10.2210/pdb1l7i/pdb |
Descriptor | chimera of Fab2C4: "humanized" murine monoclonal antibody, SULFATE ION, ... (4 entities in total) |
Functional Keywords | ig domain, fab fragment, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 47414.76 |
Authors | Vajdos, F.F.,Adams, C.W.,Breece, T.N.,Presta, L.G.,de Vos, A.M.,Sidhu, S.S. (deposition date: 2002-03-15, release date: 2002-07-10, Last modification date: 2011-07-13) |
Primary citation | Vajdos, F.F.,Adams, C.W.,Breece, T.N.,Presta, L.G.,de Vos, A.M.,Sidhu, S.S. Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis. J.Mol.Biol., 320:415-428, 2002 Cited by PubMed: 12079396DOI: 10.1016/S0022-2836(02)00264-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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