1L2H

Crystal structure of Interleukin 1-beta F42W/W120F mutant

Summary for 1L2H

• Entry DOI: 10.2210/pdb1l2h/pdb
• Related: 9ilb
• Descriptor: Interleukin 1-beta (2 entities in total)
• Functional Keywords: interleukin-1 beta, beta-trefoil, f42w/w120f double mutant, protein folding, mad phasing, hemihedral twinning, immune system
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P01584
• Total number of polymer chains: 1
• Total formula weight: 17395.83

Authors

Rudolph, M.G.,Kelker, M.S.,Schneider, T.R.,Yeates, T.O.,Oseroff, V.,Heidary, D.K.,Jennings, P.A.,Wilson, I.A. (deposition date: 2002-02-21, release date: 2003-02-04, Last modification date: 2024-02-14)

• Primary citation: Rudolph, M.G.,Kelker, M.S.,Schneider, T.R.,Yeates, T.O.,Oseroff, V.,Heidary, D.K.,Jennings, P.A.,Wilson, I.A.; Use of multiple anomalous dispersion to phase highly merohedrally twinned crystals of interleukin-1beta.; Acta Crystallogr.,Sect.D, 59:290-298, 2003; PubMed: 12554939; DOI: 10.1107/S0907444902021704

Experimental method

X-RAY DIFFRACTION (1.54 Å)