1KYI
HslUV (H. influenzae)-NLVS Vinyl Sulfone Inhibitor Complex
Summary for 1KYI
Entry DOI | 10.2210/pdb1kyi/pdb |
Related | 1G3I 1G3K 1G41 1JJW |
Descriptor | ATP-dependent hsl protease ATP-binding subunit hslU, ATP-dependent protease hslV, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | prokaryotic proteasome, protease, aaa-protein, atp-dependent chaperone; clp/hsp100, vinyl sulfone inhibitor, chaperone-hydrolase complex, chaperone/hydrolase |
Biological source | Haemophilus influenzae More |
Cellular location | Cytoplasm (By similarity): P43773 P43772 |
Total number of polymer chains | 24 |
Total formula weight | 834898.39 |
Authors | Sousa, M.C.,Kessler, B.M.,Overkleeft, H.S.,McKay, D.B. (deposition date: 2002-02-04, release date: 2002-05-15, Last modification date: 2023-08-16) |
Primary citation | Sousa, M.C.,Kessler, B.M.,Overkleeft, H.S.,McKay, D.B. Crystal Structure of HslUV Complexed with a Vinyl Sulfone Inhibitor: Corroboration of a Proposed Mechanism of Allosteric Activation of HslV by HslU J.Mol.Biol., 318:779-785, 2002 Cited by PubMed: 12054822DOI: 10.1016/S0022-2836(02)00145-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
Download full validation report