1KV6

X-ray structure of the orphan nuclear receptor ERR3 ligand-binding domain in the constitutively active conformation

1KV6 の概要

• エントリーDOI: 10.2210/pdb1kv6/pdb
• 関連するPDBエントリー: 1ERE 1K4W 3ERD
• 分子名称: ESTROGEN-RELATED RECEPTOR GAMMA, steroid receptor coactivator 1 (3 entities in total)
• 機能のキーワード: transcriptionally active conformation in absence of ligand, structural proteomics in europe, spine, structural genomics, gene regulation
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus (Probable): P62508
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 55720.89

構造登録者

Greschik, H.,Wurtz, J.-M.,Sanglier, S.,Bourguet, W.,van Dorsselaer, A.,Moras, D.,Renaud, J.-P.,Structural Proteomics in Europe (SPINE) (登録日: 2002-01-25, 公開日: 2003-01-25, 最終更新日: 2023-08-16)

• 主引用文献: Greschik, H.,Wurtz, J.-M.,Sanglier, S.,Bourguet, W.,van Dorsselaer, A.,Moras, D.,Renaud, J.-P.; Structural and Functional Evidence for Ligand-Independent Transcriptional Activation by the Estrogen-Related Receptor 3; Mol.Cell, 9:303-313, 2002; PubMed: 11864604; DOI: 10.1016/S1097-2765(02)00444-6

実験手法

X-RAY DIFFRACTION (2.7 Å)