1KOO

THE CRYSTAL STRUCTURE AND MUTATIONAL ANALYSIS OF A NOVEL RNA-BINDING DOMAIN FOUND IN THE HUMAN TAP NUCLEAR MRNA EXPORT FACTOR

Summary for 1KOO

Entry DOI	10.2210/pdb1koo/pdb
Related	1FO1 1FT8 1KOH
Descriptor	TIP ASSOCIATING PROTEIN (1 entity in total)
Functional Keywords	mrna export factor, constitutive transport element (cte), ribonucleoprotein (rnp) and leucine rich repeat (lrr) domains, rna binding protein
Biological source	Homo sapiens (human)
Cellular location	Nucleus, nucleoplasm: Q9UBU9
Total number of polymer chains	4
Total formula weight	126059.91
Authors	Ho, D.N.,Coburn, G.A.,Kang, Y.,Cullen, B.R.,Georgiadis, M.M. (deposition date: 2001-12-21, release date: 2002-02-27, Last modification date: 2023-08-16)
Primary citation	Ho, D.N.,Coburn, G.A.,Kang, Y.,Cullen, B.R.,Georgiadis, M.M. The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor. Proc.Natl.Acad.Sci.USA, 99:1888-1893, 2002 Cited by PubMed: 11854490 DOI: 10.1073/pnas.042698599 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.8 Å)

Structure validation