1K3T

Structure of Glycosomal Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi Complexed with Chalepin, a Coumarin Derivative Inhibitor

1K3T の概要

• エントリーDOI: 10.2210/pdb1k3t/pdb
• 分子名称: Glyceraldehyde-3-phosphate dehydrogenase, 6-(1,1-DIMETHYLALLYL)-2-(1-HYDROXY-1-METHYLETHYL)-2,3-DIHYDRO-7H-FURO[3,2-G]CHROMEN-7-ONE (3 entities in total)
• 機能のキーワード: apo-protein, ggapdh-chalepin complex, glycosome, trypanosoma cruzi, oxidoreductase
• 由来する生物種: Trypanosoma cruzi
• 細胞内の位置: Glycosome: P22513
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 156764.53

構造登録者

Pavao, F. (登録日: 2001-10-04, 公開日: 2002-06-19, 最終更新日: 2024-04-03)

• 主引用文献: Pavao, F.,Castilho, M.S.,Pupo, M.T.,Dias, R.L.,Correa, A.G.,Fernandes, J.B.,da Silva, M.F.,Mafezoli, J.,Vieira, P.C.,Oliva, G.; Structure of Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase complexed with chalepin, a natural product inhibitor, at 1.95 A resolution.; FEBS Lett., 520:13-17, 2002; PubMed: 12044862; DOI: 10.1016/S0014-5793(02)02700-X

実験手法

X-RAY DIFFRACTION (1.95 Å)