1JY8

2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF)

Summary for 1JY8

Entry DOI	10.2210/pdb1jy8/pdb
Descriptor	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, CYTIDINE-5'-MONOPHOSPHATE, ... (5 entities in total)
Functional Keywords	isoprenoid biosynthesis; terpenes; malaria; drug design, biosynthetic protein
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	17587.23
Authors	Steinbacher, S.,Kaiser, J.,Wungsintaweekul, J.,Hecht, S.,Eisenreich, W.,Gerhardt, S.,Bacher, A.,Rohdich, F. (deposition date: 2001-09-11, release date: 2002-01-30, Last modification date: 2024-02-07)
Primary citation	Steinbacher, S.,Kaiser, J.,Wungsintaweekul, J.,Hecht, S.,Eisenreich, W.,Gerhardt, S.,Bacher, A.,Rohdich, F. Structure of 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids. J.Mol.Biol., 316:79-88, 2002 Cited by PubMed: 11829504 DOI: 10.1006/jmbi.2001.5341 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation