1JTZ

CRYSTAL STRUCTURE OF TRANCE/RANKL CYTOKINE.

1JTZ の概要

• エントリーDOI: 10.2210/pdb1jtz/pdb
• 分子名称: TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 11 (2 entities in total)
• 機能のキーワード: tumor necrosis factor superfamily member, jellyroll, beta-sandwich, cytokine
• 由来する生物種: Mus musculus (house mouse)
• 細胞内の位置: Isoform 1: Cell membrane; Single-pass type II membrane protein. Isoform 2: Cell membrane; Single-pass type II membrane protein. Isoform 3: Cytoplasm. Tumor necrosis factor ligand superfamily member 11, soluble form: Secreted: O35235
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 57169.08

構造登録者

Nelson, C.A.,Fremont, D.H. (登録日: 2001-08-23, 公開日: 2001-09-12, 最終更新日: 2023-08-16)

• 主引用文献: Lam, J.,Nelson, C.A.,Ross, F.P.,Teitelbaum, S.L.,Fremont, D.H.; Crystal structure of the TRANCE/RANKL cytokine reveals determinants of receptor-ligand specificity; J.Clin.Invest., 108:971-979, 2001; PubMed: 11581298; DOI: 10.1172/JCI200113890

実験手法

X-RAY DIFFRACTION (2.6 Å)