1JQ6

HUMAN CYTOMEGALOVIRUS PROTEASE DIMER-INTERFACE MUTANT, S225Y

Summary for 1JQ6

Entry DOI	10.2210/pdb1jq6/pdb
Related	1JQ7 1WPO 2WPO
Descriptor	ASSEMBLIN (2 entities in total)
Functional Keywords	herpesvirus, cytomegalovirus, serine protease, dimerization, enzyme activity regulation, hydrolase
Biological source	Human herpesvirus 5 (Human cytomegalovirus)
Cellular location	Protease precursor: Host cytoplasm. Assemblin: Host nucleus. Assembly protein: Host nucleus: P16753
Total number of polymer chains	1
Total formula weight	28518.59
Authors	Batra, R.,Khayat, R.,Tong, L. (deposition date: 2001-08-03, release date: 2001-09-12, Last modification date: 2023-08-16)
Primary citation	Batra, R.,Khayat, R.,Tong, L. Molecular mechanism for dimerization to regulate the catalytic activity of human cytomegalovirus protease. Nat.Struct.Biol., 8:810-817, 2001 Cited by PubMed: 11524687 DOI: 10.1038/nsb0901-810 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation