1JKY
Crystal Structure of the Anthrax Lethal Factor (LF): Wild-type LF Complexed with the N-terminal Sequence of MAPKK2
Summary for 1JKY
Entry DOI | 10.2210/pdb1jky/pdb |
Related | 1J7N 1PWV 1PWW |
Descriptor | Lethal Factor, mitogen-activated protein kinase kinase 2 (2 entities in total) |
Functional Keywords | lethal toxin, mek2, mapkk, uncleaved substrate, protease-substrate complex, toxin |
Biological source | Bacillus anthracis More |
Cellular location | Secreted: P15917 |
Total number of polymer chains | 2 |
Total formula weight | 92150.06 |
Authors | Pannifer, A.D.,Wong, T.Y.,Schwarzenbacher, R.,Renatus, M.,Petosa, C.,Collier, R.J.,Bienkowska, J.,Lacy, D.B.,Park, S.,Leppla, S.H.,Hanna, P.,Liddington, R.C. (deposition date: 2001-07-13, release date: 2001-11-07, Last modification date: 2023-08-16) |
Primary citation | Pannifer, A.D.,Wong, T.Y.,Schwarzenbacher, R.,Renatus, M.,Petosa, C.,Bienkowska, J.,Lacy, D.B.,Collier, R.J.,Park, S.,Leppla, S.H.,Hanna, P.,Liddington, R.C. Crystal structure of the anthrax lethal factor. Nature, 414:229-233, 2001 Cited by PubMed: 11700563DOI: 10.1038/n35101998 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.9 Å) |
Structure validation
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