1JBU
Coagulation Factor VII Zymogen (EGF2/Protease) in Complex with Inhibitory Exosite Peptide A-183
Summary for 1JBU
Entry DOI | 10.2210/pdb1jbu/pdb |
Related | 1CVW 1DAN 1DVA 1FAK 1QFK |
Descriptor | COAGULATION FACTOR VII, Peptide exosite inhibitor A-183, SULFATE ION, ... (6 entities in total) |
Functional Keywords | shifted registration, beta-strands, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P08709 P08709 |
Total number of polymer chains | 3 |
Total formula weight | 37191.41 |
Authors | Eigenbrot, C.,Kirchhofer, D.,Dennis, M.S.,Santell, L.,Lazarus, R.A.,Stamos, J.,Ultsch, M.H. (deposition date: 2001-06-06, release date: 2001-07-11, Last modification date: 2023-08-16) |
Primary citation | Eigenbrot, C.,Kirchhofer, D.,Dennis, M.S.,Santell, L.,Lazarus, R.A.,Stamos, J.,Ultsch, M.H. The factor VII zymogen structure reveals reregistration of beta strands during activation. Structure, 9:627-636, 2001 Cited by PubMed: 11470437DOI: 10.1016/S0969-2126(01)00624-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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