1JAP

COMPLEX OF PRO-LEU-GLY-HYDROXYLAMINE WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM)

1JAP の概要

• エントリーDOI: 10.2210/pdb1jap/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000404
• 分子名称: MATRIX METALLO PROTEINASE-8 (MET80 FORM), PRO-LEU-GLY-HYDROXYLAMINE, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: metalloprotease, zinc-endopeptidase, metzincins, complex (metalloprotease-inhibitor) complex, complex (metalloprotease/inhibitor)
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasmic granule: P22894
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 18623.07

構造登録者

Bode, W.,Reinemer, P.,Huber, R.,Kleine, T.,Schnierer, S.,Tschesche, H. (登録日: 1996-03-11, 公開日: 1996-07-11, 最終更新日: 2024-06-05)

• 主引用文献: Bode, W.,Reinemer, P.,Huber, R.,Kleine, T.,Schnierer, S.,Tschesche, H.; The X-ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity.; EMBO J., 13:1263-1269, 1994; PubMed: 8137810

実験手法

X-RAY DIFFRACTION (1.82 Å)