1JAN
COMPLEX OF PRO-LEU-GLY-HYDROXYLAMINE WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (PHE79 FORM)
Summary for 1JAN
Entry DOI | 10.2210/pdb1jan/pdb |
Related PRD ID | PRD_000404 |
Descriptor | MATRIX METALLO PROTEINASE-8 (PHE79 FORM), PRO-LEU-GLY-HYDROXYLAMINE INHIBITOR, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | metalloprotease, zinc-endopeptidase, metzincins, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasmic granule: P22894 |
Total number of polymer chains | 2 |
Total formula weight | 18770.25 |
Authors | Reinemer, P.,Grams, F.,Huber, R.,Kleine, T.,Schnierer, S.,Pieper, M.,Tschesche, H.,Bode, W. (deposition date: 1996-03-11, release date: 1996-07-11, Last modification date: 2024-06-05) |
Primary citation | Reinemer, P.,Grams, F.,Huber, R.,Kleine, T.,Schnierer, S.,Piper, M.,Tschesche, H.,Bode, W. Structural implications for the role of the N terminus in the 'superactivation' of collagenases. A crystallographic study. FEBS Lett., 338:227-233, 1994 Cited by PubMed: 8307185DOI: 10.1016/0014-5793(94)80370-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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