1JAI
H-RAS P21 PROTEIN MUTANT G12P, COMPLEXED WITH GUANOSINE-5'-[BETA,GAMMA-METHYLENE] TRIPHOSPHATE AND MANGANESE
Summary for 1JAI
Entry DOI | 10.2210/pdb1jai/pdb |
Descriptor | C-HA-RAS, MANGANESE (II) ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... (4 entities in total) |
Functional Keywords | gtp hydrolysis, signal transduction, cancer, g-domain, gtp-binding |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side: P01112 |
Total number of polymer chains | 1 |
Total formula weight | 19491.40 |
Authors | Schweins, T.,Scheffzek, K.,Assheuer, R.,Wittinghofer, A. (deposition date: 1996-12-15, release date: 1997-07-23, Last modification date: 2024-04-03) |
Primary citation | Schweins, T.,Scheffzek, K.,Assheuer, R.,Wittinghofer, A. The role of the metal ion in the p21ras catalysed GTP-hydrolysis: Mn2+ versus Mg2+. J.Mol.Biol., 266:847-856, 1997 Cited by PubMed: 9102473DOI: 10.1006/jmbi.1996.0814 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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