1J96
Human 3alpha-HSD type 3 in Ternary Complex with NADP and Testosterone
Summary for 1J96
Entry DOI | 10.2210/pdb1j96/pdb |
Descriptor | 3alpha-hydroxysteroid dehydrogenase type 3, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total) |
Functional Keywords | aldo-keto reductase, steroid metabolism, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (Potential): P52895 |
Total number of polymer chains | 2 |
Total formula weight | 75722.07 |
Authors | Nahoum, V.,Labrie, F.,Lin, S.-X. (deposition date: 2001-05-23, release date: 2002-05-23, Last modification date: 2023-08-16) |
Primary citation | Nahoum, V.,Gangloff, A.,Legrand, P.,Zhu, D.W.,Cantin, L.,Zhorov, B.S.,Luu-The, V.,Labrie, F.,Breton, R.,Lin, S.X. Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution. J.Biol.Chem., 276:42091-42098, 2001 Cited by PubMed: 11514561DOI: 10.1074/jbc.M105610200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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