1J59

CATABOLITE GENE ACTIVATOR PROTEIN (CAP)/DNA COMPLEX + ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE

「1BER」から置き換えられました

1J59 の概要

• エントリーDOI: 10.2210/pdb1j59/pdb
• 分子名称: 5'-D(*GP*CP*GP*AP*AP*AP*AP*GP*TP*GP*TP*GP*AP*C)-3', 5'-D(*AP*TP*AP*TP*GP*TP*CP*AP*CP*AP*CP*TP*TP*TP*TP*CP*G )-3', CATABOLITE GENE ACTIVATOR PROTEIN (CAP), ... (5 entities in total)
• 機能のキーワード: protein-dna complex, gene-regulatory, gene regulation-dna complex, gene regulation/dna
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 66753.32

構造登録者

Parkinson, G.,Wilson, C.,Gunasekera, A.,Ebright, Y.W.,Ebright, R.H.,Berman, H.M. (登録日: 2002-03-01, 公開日: 2002-03-01, 最終更新日: 2023-12-27)

主引用文献

Parkinson, G.,Wilson, C.,Gunasekera, A.,Ebright, Y.W.,Ebright, R.E.,Berman, H.M.
Structure of the CAP-DNA complex at 2.5 angstroms resolution: a complete picture of the protein-DNA interface.
J.Mol.Biol., 260:395-408, 1996

PubMed Abstract: The crystallographic structure of the CAP-DNA complex at 3.0 A resolution has been reported previously. For technical reasons, the reported structure had been determined using a gapped DNA molecule lacking two phosphates important for CAP-DNA interaction. In this work, we report the crystallographic structure of the CAP-DNA complex at 2.5 A resolution using a DNA molecule having all phosphates important for CAP-DNA interaction. The present resolution permits unambiguous identification of amino acid-base and amino acid-phosphate hydrogen bonded contacts in the CAP-DNA complex. In addition, the present resolution permits accurate definition of the kinked DNA conformation in the CAP-DNA complex.

PubMed: 8757802
DOI: 10.1006/jmbi.1996.0409

実験手法

X-RAY DIFFRACTION (2.5 Å)