1J49

INSIGHTS INTO DOMAIN CLOSURE, SUBSTRATE SPECIFICITY AND CATALYSIS OF D-LACTATE DEHYDROGENASE FROM LACTOBACILLUS BULGARICUS

Summary for 1J49

Entry DOI	10.2210/pdb1j49/pdb
Descriptor	D-LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... (4 entities in total)
Functional Keywords	nad-dependent dehydrogenase, last step of glycolysis under anaerobic conditions, reversible interconversion of pyruvate into d-lactate, oxidoreductase
Biological source	Lactobacillus delbrueckii subsp. bulgaricus
Total number of polymer chains	2
Total formula weight	75665.16
Authors	Razeto, A.,Kochhar, S.,Hottinger, H.,Dauter, M.,Wilson, K.S.,Lamzin, V.S. (deposition date: 2001-08-14, release date: 2002-05-29, Last modification date: 2023-08-16)
Primary citation	Razeto, A.,Kochhar, S.,Hottinger, H.,Dauter, M.,Wilson, K.S.,Lamzin, V.S. Domain closure, substrate specificity and catalysis of D-lactate dehydrogenase from Lactobacillus bulgaricus. J.Mol.Biol., 318:109-119, 2002 Cited by PubMed: 12054772 DOI: 10.1016/S0022-2836(02)00086-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation