1IY7
Crystal Structure of CPA and sulfamide-based inhibitor complex
Summary for 1IY7
| Entry DOI | 10.2210/pdb1iy7/pdb |
| Descriptor | Carboxypeptidase A, ZINC ION, PHENYLALANINE-N-SULFONAMIDE, ... (4 entities in total) |
| Functional Keywords | protein-inhibitor complex, hydrolase |
| Biological source | Bos taurus (cattle) |
| Cellular location | Secreted, extracellular space: P00730 |
| Total number of polymer chains | 1 |
| Total formula weight | 34752.14 |
| Authors | Kim, S.J.,Woo, J.R.,Park, J.D.,Kim, D.H.,Ryu, S.E. (deposition date: 2002-07-24, release date: 2003-01-28, Last modification date: 2023-12-27) |
| Primary citation | Park, J.D.,Kim, D.H.,Kim, S.J.,Woo, J.R.,Ryu, S.E. Sulfamide-Based Inhibitors for Carboxypeptidase A. Novel Type Transition State Analogue Inhibitors for Zinc Proteases J.Med.Chem., 45:5295-5302, 2002 Cited by PubMed: 12431056DOI: 10.1021/jm020258v PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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