1IXX

CRYSTAL STRUCTURE OF COAGULATION FACTORS IX/X-BINDING PROTEIN (IX/X-BP) FROM VENOM OF HABU SNAKE WITH A HETERODIMER OF C-TYPE LECTIN DOMAINS

Summary for 1IXX

• Entry DOI: 10.2210/pdb1ixx/pdb
• Descriptor: COAGULATION FACTORS IX/X-BINDING PROTEIN, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: coagulation factor binding, c-type lectin, gla-domain binding, c-type crd motif, loop exchanged dimer
• Biological source: Trimeresurus flavoviridis; More
• Cellular location: Secreted: P23806 P23807
• Total number of polymer chains: 6
• Total formula weight: 88142.22

Authors

Mizuno, H.,Fujimoto, Z.,Koizumi, M.,Kano, H. (deposition date: 1997-05-01, release date: 1998-05-06, Last modification date: 2024-10-30)

Primary citation

Mizuno, H.,Fujimoto, Z.,Koizumi, M.,Kano, H.,Atoda, H.,Morita, T.
Structure of coagulation factors IX/X-binding protein, a heterodimer of C-type lectin domains.
Nat.Struct.Biol., 4:438-441, 1997

PubMed Abstract: Coagulation factors IX/X-binding protein is an intertwined dimer with a central loop projecting into the adjoining subunit. Excluding this loop, each subunit has a fold similar to rat mannose-binding protein.

PubMed: 9187649
DOI: 10.1038/nsb0697-438

Experimental method

X-RAY DIFFRACTION (2.5 Å)