1IV1

Structure of 2C-Methyl-D-erythritol-2,4-cyclodiphosphate Synthase

Summary for 1IV1

• Entry DOI: 10.2210/pdb1iv1/pdb
• Related: 1IV2 1IV3 1IV4
• Descriptor: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (2 entities in total)
• Functional Keywords: isoprenoid, non-mevalonate, synthase, riken structural genomics/proteomics initiative, rsgi, structural genomics, lyase
• Biological source: Thermus thermophilus
• Total number of polymer chains: 6
• Total formula weight: 99264.47

Authors

Kishida, H.,Wada, T.,Unzai, S.,Kuzuyama, T.,Terada, T.,Sirouzu, M.,Yokoyama, S.,Tame, J.R.H.,Park, S.-Y.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2002-03-11, release date: 2002-09-11, Last modification date: 2023-12-27)

• Primary citation: Kishida, H.,Wada, T.,Unzai, S.,Kuzuyama, T.,Takagi, M.,Terada, T.,Shirouzu, M.,Yokoyama, S.,Tame, J.R.,Park, S.Y.; Structure and catalytic mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MECDP) synthase, an enzyme in the non-mevalonate pathway of isoprenoid synthesis.; Acta Crystallogr.,Sect.D, 59:23-31, 2003; PubMed: 12499535; DOI: 10.1107/S0907444902017705

Experimental method

X-RAY DIFFRACTION (1.65 Å)