1ITG

CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HIV-1 INTEGRASE: SIMILARITY TO OTHER POLYNUCLEOTIDYL TRANSFERASES

1ITG の概要

• エントリーDOI: 10.2210/pdb1itg/pdb
• 分子名称: HIV-1 INTEGRASE, CACODYLATE ION (3 entities in total)
• 機能のキーワード: dna integration, dna binding (viral)
• 由来する生物種: Human immunodeficiency virus 1
• 細胞内の位置: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18468.74

構造登録者

Dyda, F.,Hickman, A.B.,Jenkins, T.M.,Engelman, A.,Craigie, R.,Davies, D.R. (登録日: 1994-11-21, 公開日: 1995-05-08, 最終更新日: 2024-02-07)

• 主引用文献: Dyda, F.,Hickman, A.B.,Jenkins, T.M.,Engelman, A.,Craigie, R.,Davies, D.R.; Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases.; Science, 266:1981-1986, 1994; PubMed: 7801124

実験手法

X-RAY DIFFRACTION (2.3 Å)