1ISO

ISOCITRATE DEHYDROGENASE: STRUCTURE OF AN ENGINEERED NADP+--> NAD+ SPECIFICITY-REVERSAL MUTANT

Summary for 1ISO

Entry DOI	10.2210/pdb1iso/pdb
Descriptor	ISOCITRATE DEHYDROGENASE, SULFATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
Functional Keywords	nadp, phosphorylation, glyoxylate bypass, oxidoreductase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	46652.99
Authors	Hurley, J.H. (deposition date: 1996-03-01, release date: 1996-12-07, Last modification date: 2023-08-09)
Primary citation	Hurley, J.H.,Chen, R.,Dean, A.M. Determinants of cofactor specificity in isocitrate dehydrogenase: structure of an engineered NADP+ --> NAD+ specificity-reversal mutant. Biochemistry, 35:5670-5678, 1996 Cited by PubMed: 8639526 DOI: 10.1021/bi953001q PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation