1IM3

Crystal Structure of the human cytomegalovirus protein US2 bound to the MHC class I molecule HLA-A2/tax

1IM3 の概要

• エントリーDOI: 10.2210/pdb1im3/pdb
• 分子名称: HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, beta-2-microglobulin, Human T-cell lymphotropic virus type 1 Tax peptide, ... (5 entities in total)
• 機能のキーワード: beta sheet, beta sandwhich, immunoglobulin (ig) fold, immunoglobulin (ig)-like domain, protein complex, alpha helix, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769; Host endoplasmic reticulum membrane; Single- pass type I membrane protein: P09713
• タンパク質・核酸の鎖数: 16
• 化学式量合計: 222813.10

構造登録者

Gewurz, B.E.,Gaudet, R.,Tortorella, D.,Wang, E.W.,Ploegh, H.L.,Wiley, D.C. (登録日: 2001-05-09, 公開日: 2001-06-06, 最終更新日: 2023-08-16)

• 主引用文献: Gewurz, B.E.,Gaudet, R.,Tortorella, D.,Wang, E.W.,Ploegh, H.L.,Wiley, D.C.; Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2.; Proc.Natl.Acad.Sci.USA, 98:6794-6799, 2001; PubMed: 11391001; DOI: 10.1073/pnas.121172898

実験手法