1IHH

2.4 ANGSTROM CRYSTAL STRUCTURE OF AN OXALIPLATIN 1,2-D(GPG) INTRASTRAND CROSS-LINK IN A DNA DODECAMER DUPLEX

Summary for 1IHH

• Entry DOI: 10.2210/pdb1ihh/pdb
• Descriptor: 5'-D(*CP*CP*TP*CP*TP*GP*GP*TP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*AP*CP*CP*AP*GP*AP*GP*G)-3', PLATINUM (II) ION, ... (6 entities in total)
• Functional Keywords: right handed dna, double helix, complexed with drug, oxaliplatin, modified, deoxynucleic acid, dna
• Total number of polymer chains: 2
• Total formula weight: 7773.38

Authors

Spingler, B.,Whittington, D.A.,Lippard, S.J. (deposition date: 2001-04-19, release date: 2001-10-26, Last modification date: 2024-02-07)

• Primary citation: Spingler, B.,Whittington, D.A.,Lippard, S.J.; 2.4 A crystal structure of an oxaliplatin 1,2-d(GpG) intrastrand cross-link in a DNA dodecamer duplex.; Inorg.Chem., 40:5596-5602, 2001; PubMed: 11599959; DOI: 10.1021/ic010790t

Experimental method

X-RAY DIFFRACTION (2.4 Å)