1IEZ

Solution Structure of 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase of Riboflavin Biosynthesis

1IEZ の概要

• エントリーDOI: 10.2210/pdb1iez/pdb
• 関連するPDBエントリー: 1g57 1g58
• 分子名称: 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase (1 entity in total)
• 機能のキーワード: dihydroxybutanone phosphate synthase, riboflavin biosynthesis, skeletal rearrangement, antimicrobial target, structure based design, isomerase
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cell membrane; Peripheral membrane protein (Potential): P0A7J0
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23378.46

構造登録者

Kelly, M.J.S.,Ball, L.J.,Kuhne, R.,Bacher, A.,Oschkinat, H. (登録日: 2001-04-11, 公開日: 2001-11-07, 最終更新日: 2024-05-01)

• 主引用文献: Kelly, M.J.,Ball, L.J.,Krieger, C.,Yu, Y.,Fischer, M.,Schiffmann, S.,Schmieder, P.,Kuhne, R.,Bermel, W.,Bacher, A.,Richter, G.,Oschkinat, H.; The NMR structure of the 47-kDa dimeric enzyme 3,4-dihydroxy-2-butanone-4-phosphate synthase and ligand binding studies reveal the location of the active site.; Proc.Natl.Acad.Sci.USA, 98:13025-13030, 2001; PubMed: 11687623; DOI: 10.1073/pnas.231323598

実験手法

SOLUTION NMR