1IEC

CRYSTAL STRUCTURE OF THE CATALYTIC SITE MUTANT (H157A) OF THE HUMAN CYTOMEGALOVIRUS PROTEASE

Summary for 1IEC

Entry DOI	10.2210/pdb1iec/pdb
Related	1ID4 1IED 1IEF 1IEG 1WPO 2WPO
Descriptor	CAPSID PROTEIN P40: ASSEMBLIN PROTEASE (2 entities in total)
Functional Keywords	coat protein, hydrolase, serine protease, catalytic triad, viral protease
Biological source	Human herpesvirus 5
Cellular location	Protease precursor: Host cytoplasm. Assemblin: Host nucleus. Assembly protein: Host nucleus: P16753
Total number of polymer chains	2
Total formula weight	56435.33
Authors	Khayat, R.,Batra, R.,Massariol, M.J.,Lagace, L.,Tong, L. (deposition date: 2001-04-09, release date: 2001-06-06, Last modification date: 2023-08-09)
Primary citation	Khayat, R.,Batra, R.,Massariol, M.J.,Lagace, L.,Tong, L. Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease. Biochemistry, 40:6344-6351, 2001 Cited by PubMed: 11371196 DOI: 10.1021/bi010158b PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation