1IDB
Crystal structures of HIV-2 protease in complex with inhibitors containing the hydroxyethylamine dipeptide isostere
Summary for 1IDB
Entry DOI | 10.2210/pdb1idb/pdb |
Related | 1IDA |
Related PRD ID | PRD_000244 |
Descriptor | Protease, (2R,4S)-N-tert-butyl-1-[(2S,3S)-3-{[(2,6-dimethylphenoxy)acetyl]amino}-2-hydroxy-4-phenylbutyl]-4-(pyridin-4-ylsulfonyl)piperidine-2-carboxamide (3 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human immunodeficiency virus 2 |
Total number of polymer chains | 2 |
Total formula weight | 22107.50 |
Authors | Tong, L.,Anderson, P.C. (deposition date: 1994-10-19, release date: 1995-01-26, Last modification date: 2024-02-07) |
Primary citation | Tong, L.,Pav, S.,Mui, S.,Lamarre, D.,Yoakim, C.,Beaulieu, P.,Anderson, P.C. Crystal structures of HIV-2 protease in complex with inhibitors containing the hydroxyethylamine dipeptide isostere. Structure, 3:33-40, 1995 Cited by PubMed: 7743130DOI: 10.1016/S0969-2126(01)00133-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report