1ICA

REFINED THREE-DIMENSIONAL STRUCTURE OF INSECT DEFENSIN A

1ICA の概要

• エントリーDOI: 10.2210/pdb1ica/pdb
• 分子名称: INSECT DEFENSIN A (1 entity in total)
• 機能のキーワード: antibacterial protein
• 由来する生物種: Protophormia terraenovae
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 4072.69

構造登録者

Cornet, B.,Bonmatin, J.M.,Ptak, M.,Vovelle, F. (登録日: 1994-12-16, 公開日: 1995-07-10, 最終更新日: 2024-10-09)

主引用文献

Cornet, B.,Bonmatin, J.M.,Hetru, C.,Hoffmann, J.A.,Ptak, M.,Vovelle, F.
Refined three-dimensional solution structure of insect defensin A.
Structure, 3:435-448, 1995

PubMed Abstract: Insect defensin A is a basic 4 kDa protein secreted by Phormia terranovae larvae in response to bacterial challenges or injuries. Previous biological tests suggest that the bacterial cytoplasmic membrane is the target of defensin A. The structural study of this protein is the first step towards establishing a structure-activity relationship and forms the basis for understanding its antibiotic activity at the molecular level.

PubMed: 7663941
DOI: 10.1016/S0969-2126(01)00177-0

実験手法

SOLUTION NMR