1IC8
HEPATOCYTE NUCLEAR FACTOR 1A BOUND TO DNA : MODY3 GENE PRODUCT
Summary for 1IC8
Entry DOI | 10.2210/pdb1ic8/pdb |
Related | 1AU7 1LFB 1OCT 2LFB |
Descriptor | 5'-D(*CP*TP*TP*GP*GP*TP*TP*AP*AP*TP*AP*AP*TP*TP*CP*AP*CP*CP*AP*GP*A)-3', 5'-D(*TP*CP*TP*GP*GP*TP*GP*AP*AP*TP*TP*AP*TP*TP*AP*AP*CP*CP*AP*AP*G)-3', HEPATOCYTE NUCLEAR FACTOR 1-ALPHA, ... (4 entities in total) |
Functional Keywords | transcription regulation; dna-binding; pou domain; diabetes; disease mutation; mody3, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : P20823 |
Total number of polymer chains | 4 |
Total formula weight | 57857.03 |
Authors | Chi, Y.-I.,Frantz, J.D.,Oh, B.-C.,Hansen, L.,Dhe-Paganon, S.,Shoelson, S.E. (deposition date: 2001-03-30, release date: 2002-11-27, Last modification date: 2024-02-07) |
Primary citation | Chi, Y.-I.,Frantz, J.D.,Oh, B.-C.,Hansen, L.,Dhe-Paganon, S.,Shoelson, S.E. Diabetes mutations delineate an atypical POU domains in HNF1-Alpha Mol.Cell, 10:1129-1137, 2002 Cited by PubMed: 12453420DOI: 10.1016/S1097-2765(02)00704-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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