1I9D

ARSENATE REDUCTASE FROM E. COLI

Summary for 1I9D

• Entry DOI: 10.2210/pdb1i9d/pdb
• Descriptor: ARSENATE REDUCTASE, SULFATE ION, SULFITE ION, ... (5 entities in total)
• Functional Keywords: arsenic, arsenate, reductase, oxidoreductase
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 17546.54

Authors

Martin, P.,Edwards, B.F. (deposition date: 2001-03-19, release date: 2001-12-05, Last modification date: 2024-02-07)

Primary citation

Martin, P.,DeMel, S.,Shi, J.,Gladysheva, T.,Gatti, D.L.,Rosen, B.P.,Edwards, B.F.
Insights into the structure, solvation, and mechanism of ArsC arsenate reductase, a novel arsenic detoxification enzyme.
Structure, 9:1071-1081, 2001

PubMed Abstract: In Escherichia coli bearing the plasmid R773, resistance to arsenite, arsenate, antimonite, and tellurite is conferred by the arsRDABC plasmid operon that codes for an ATP-dependent anion pump. The product of the arsC gene, arsenate reductase (ArsC), is required to efficiently catalyze the reduction of arsenate to arsenite prior to extrusion.

PubMed: 11709171
DOI: 10.1016/S0969-2126(01)00672-4

Experimental method

X-RAY DIFFRACTION (1.65 Å)